期刊
JOURNAL OF MATERIALS CHEMISTRY
卷 19, 期 35, 页码 6308-6316出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b904197d
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资金
- NCI NIH HHS [R01 CA133697-02, R01 CA133697] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [R01CA133697] Funding Source: NIH RePORTER
The transport of nucleic acid-based reagents is predicated upon developing structurally stable delivery systems that can preferentially bind and protect DNA and RNA, and release their cargo upon reaching their designated sites. Recent advancements in tailoring the size, shape, and external surface functionalization of silica materials have led to increased biocompatibility and efficiency of delivery. In this Feature Article, we highlight recent research progress in the use of silica nanoparticles as a delivery vehicle for nucleic acid-based reagents.
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