期刊
JOURNAL OF MATERIALS CHEMISTRY
卷 18, 期 31, 页码 3655-3661出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b805366a
关键词
-
Calcium phosphate nanoparticles were prepared by precipitation and colloidally stabilized by surface functionalization with 5,10,15,20- tetrakis( 4- phosphonooxyphenyl) porphine ( p- TPPP). No other stabilizing agents were necessary, and all dissolved counter- ions and excess porphyrin were removed by ultracentrifugation. The resulting porphyrin- functionalized nanoparticles were spherical with a diameter of about 250 nm. The adsorption of porphyrin on the calcium phosphate surface was confirmed by IR spectroscopy and quantified by elemental analysis ( the loading was about 4 - 5 wt% porphyrin). In a cell culture with NIH 3T3 fibroblast cells, the particles showed excellent biocompatibility ( confirmed by an MTT test), and their uptake into the cells could be followed by confocal laser scanning microscopy. Hence, these biocompatible nanoparticles may be used as biocompatible fluorescing agents or for the delivery of fluorescing molecules.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据