期刊
JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 34, 期 2, 页码 384-394出版社
WILEY-BLACKWELL
DOI: 10.1002/jmri.22628
关键词
carotid angiography; arterial spin labeling; pulsed ASL; pseudocontinuous ASL; MRA
资金
- American Heart Association [0835367N]
- Grainger Foundation
- Auxiliary of North Shore University Health System
Purpose: To compare pulsed arterial spin labeling (PASL) and pseudocontinuous arterial spin labeling (PCASL) for nonenhanced extracranial carotid MR angiography (MRA). Materials and Methods: Parametric signal equations for PASL and PCASL MRA were formulated and compared. Volunteer imaging (n = 7) at 1.5 Tesla was performed to compare the methods over a broad range of repetition and labeling times. Empirical results were compared with theoretical predictions. The feasibility of the optimal method was investigated in patients (n = 2) with sonographically documented carotid artery disease. Results: In volunteers, PCASL provided significantly improved signal than PASL (range: 32-255% improvement; P < 0.01), and better supported the use of long labeling times and short repetition times. Excellent agreement between theory and experiment was found (intraclass correlation coefficient = 0.966; P < 0.001). PCASL provided excellent depiction of the carotid arteries in initial patient studies. Conclusion: Compared with pulsed tagging, pseudocontinuous tagging provides improved performance for nonenhanced extracranial carotid MRA and warrants further clinical investigation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据