期刊
JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 31, 期 3, 页码 673-679出版社
WILEY
DOI: 10.1002/jmri.22091
关键词
MRI; dynamic study; diffusion-weighted imaging; salivary gland tumor; malignant; benign
资金
- Grants-in-Aid for Scientific Research [21592391] Funding Source: KAKEN
Purpose: To evaluate the stepwise approach in differentiating between benign and malignant salivary gland tumors using time-intensity curves (TICs) and apparent diffusion coefficients (ADCs). Materials and Methods: TICs and ADCs were analyzed on the tumor-by-tumor (overall) and pixel-by-pixel (TIC and ADC maps) bases in patients with benign (n = 52) or malignant (n = 18) salivary gland tumor. TICs were categorized into Types 1 (<20% increment ratio), 2 (>= 20% increment ratio and >120 see peak time), 3 (>= 20% increment ratio, <= 120 see peak time, and <30% washout ratio), or 4 (>= 20% increment ratio, <= 120 see peak time, and >= 30% washout ratio). ADCs were classified as extremely low (<0.6 x 10(-3) mm(2)/sec), low (<1.2), intermediate (<1.8), or high (>= 1.8). Results: Malignant tumors had small (<30%) areas with Type 1 TIC with one of the following magnetic resonance imaging (MRI) characteristics: Type 3 overall TIC patterns, Type 4 overall TIC patterns and extremely low (<0.60 x 10(-3) mm(2)/sec) overall ADCs, or Type 2 overall TIC patterns and large (>40%) areas with low or extremely low ADCs. Conclusion: We propose a stepwise approach by using multiparametric MRI techniques as an effective tool for differentiating between benign and malignant salivary gland tumors
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