期刊
JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 29, 期 5, 页码 1154-1162出版社
WILEY
DOI: 10.1002/jmri.21746
关键词
whole-body MRI; cancer metastases; fast Dixon sequences; multisequence imaging; multiplanar imaging
Purpose: To develop and demonstrate the feasibility of multisequence and multiplanar MRI for whole-body cancer detection. Materials and Methods: Two fast Dixon-based sequences and a diffusion-weighted sequence were used on a commercially available 1.5 T scanner for whole-body cancer detection. The study enrolled 19 breast cancer patients with known metastases and in multistations acquired whole-body axial diffusion-weighted, coronal T2-weighted, axial/sagittal pre- and postcontrast T1-weighted, as well as triphasic abdomen images. Three radiologists subjectively scored Dixon images of each series for overall image quality and fat suppression uniformity on a 4-point scale (1 = poor, 2 = fair, 3 = good, and 4 = excellent). Results: Eighteen of the 19 patients completed the whole-body MRI successfully. The mean acquisition time and overall patient table time were 46 +/- 3 and 69 +/- 5 minutes, respectively. The average radiologists' scores for overall image quality and fat Suppression uniformity were both 3.4 +/- 0.5. The image quality was consistent between patients and all completed whole-body examinations were diagnostically adequate. Conclusion: Whole-body MRI offering essentially all the most optimal tumor-imaging sequences in a typical 1-hour time slot can potentially become an appealing one-stop-shop for whole-body cancer imaging.
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