相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D3 action
J. Wesley Pike et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
Vitamin D 25-hydroxylase - Four decades of searching, are we there yet?
Jinge Zhu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D
Glenville Jones et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
Hypercalcemia, Hypercalciuria, and Elevated Calcitriol Concentrations with Autosomal Dominant Transmission Due to CYP24A1 Mutations: Effects of Ketoconazole Therapy
Peter J. Tebben et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Genetic Defect in CYP24A1, the Vitamin D 24-Hydroxylase Gene, in a Patient with Severe Infantile Hypercalcemia
Andrew Dauber et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D3
Steve Y. Rhieu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
CYP24A1 Is an Independent Prognostic Marker of Survival in Patients with Lung Adenocarcinoma
Guoan Chen et al.
CLINICAL CANCER RESEARCH (2011)
CYP24A1 and kidney disease
Martin Petkovich et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2011)
Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation
Martin Kaufmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
CYP24A1Mutations in Idiopathic Infantile Hypercalcemia
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Mutations in CYP24A1 and Idiopathic Infantile Hypercalcemia
Karl P. Schlingmann et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge
Ingemar Bjorkhem et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Vitamin D Analogs
Glenville Jones
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2010)
Genetic Disorders and Defects in Vitamin D Action
Peter J. Malloy et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2010)
Fibroblast growth factor 23 and its role in phosphate homeostasis
Isolde Ramon et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2010)
Update in Vitamin D
John S. Adams et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
The Candidate Oncogene CYP24A1: A Potential Biomarker for Colorectal Tumorigenesis
Henrik C. Horvath et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2010)
Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism
Andrew J. Annalora et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Epigenetic silencing of CYP24 in the tumor microenvironment
Candace S. Johnson et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
CYP24A1-deficient mice as a tool to uncover a biological activity for vitamin D metabolites hydroxylated at position 24
Rene St-Arnaud
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
Cholecalciferol Supplementation Alters Calcitriol-Responsive Monocyte Proteins and Decreases Inflammatory Cytokines in ESRD
Jason R. Stubbs et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Common genetic determinants of vitamin D insufficiency: a genome-wide association study
Thomas J. Wang et al.
LANCET (2010)
Relation between serum fibroblast growth factor-23 level and mortality in incident dialysis patients: are gender and cardiovascular disease confounding the relationship?
Hannes Olauson et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2010)
Crystallization and preliminary X-ray diffraction studies of vitamin D-3 hydroxylase, a novel cytochrome P450 isolated from Pseudonocardia autotrophica
Yoshiaki Yasutake et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2009)
Metabolism of 1α,25-dihydroxyvitamin D2 by human CYP24A1
Naoko Urushino et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Chondrocyte-Specific Modulation of Cyp27b1 Expression Supports a Role for Local Synthesis of 1,25-Dihydroxyvitamin D3 in Growth Plate Development
Roy Pascal Naja et al.
ENDOCRINOLOGY (2009)
Crystal structure of CYP105A1 (P450SU-1) in complex with 1α,25-dihydroxyvitamin D3
Hiroshi Sugimoto et al.
BIOCHEMISTRY (2008)
Vitamin D-Binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo
J. Wesley Pike et al.
ENDOCRINOLOGY (2008)
Physiological regulation and disorders of phosphate metabolism - Pivotal role of fibroblast growth factor 23
Seiji Fukumoto
INTERNAL MEDICINE (2008)
Structural analysis of CYP2R1 in complex with vitamin D3
Naltallia Strushkevich et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
25 hydroxy-vitamin D3-1α hydroxylase expression and activity in cultured human osteoblasts and their modulation by parathyroid hormone, estrogenic compounds and dihydrotestosterone
Dalia Somjen et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1α-hydroxylase expression in vitro
Farzana Perwad et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Vitamin D 1α-hydroxylase gene mutations in patients with 1α-hydroxylase deficiency
Chan Jong Kim et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into-23-hydroxylase, generating 1α,25-(OH)2D3-26,23-lactone
David E. Prosser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Vitamin D deficiency
Michael F. Holick
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production
S. Wu et al.
ENDOCRINOLOGY (2007)
The emerging role of the fibroblast growth factor-23-Klotho axis in renal regulation of phosphate homeostasis
Mohammed S. Razzaque et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Expanding role for vitamin D in chronic kidney disease:: Importance of blood 25-OH-D levels and extra-renal 1α-hydroxylase in the classical and nonclassical actions of 1α,25-dihydroxyvitamin D3
Glenville Jones
SEMINARS IN DIALYSIS (2007)
Phenobarbital suppresses vitamin D3 25-hydroxylase expression:: A potential new mechanism for drug-induced osteomalacia
Fardin Hosseinpour et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
How fibroblast growth factor 23 works
Shiguang Liu et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies
Sonoko Masuda et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: Insights into substrate specificity and membrane bound structure-function
Andrew J. Annalora et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Homology model of 1α,25-dihydroxyvitamin D3 24-hydroxylase cytochrome P450 24A1 (CYP24A1):: Active site architecture and ligand binding
Mohamed Sayed Gomaa et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism
Jurgen Schauber et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas
Silke Lassmann et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
被撤回的出版物: 1α,25(OH)2D3-induced DNA methylation suppresses the human CYP27B1 gene (Retracted article. See vol. 424, pg. 128, 2016)
Mi-Sun Kim et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2007)
CYP24, the enzyme that catabolizes the antiproliferative agent vitamin D, is increased in lung cancer
Robert A. Parise et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Immune regulation of 25-hydroxyvitamin D-1α-hydroxylase in human monocytic THP1 cells:: Mechanisms of interferon-γ-mediated induction
Lut Overbergh et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: Amino acid residues responsible for species-based difference of CYP24A1 between humans and rats
Hiromi Hamamoto et al.
MOLECULAR PHARMACOLOGY (2006)
Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation
DE Prosser et al.
BIOPHYSICAL JOURNAL (2006)
Distinct binding of cholesterol and 5-cholestane-3α,7α,12α-triol to cytochrome P450 27A1:: Evidence from modeling and site-directed mutagenesis studies
N Mast et al.
BIOCHEMISTRY (2006)
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
PT Liu et al.
SCIENCE (2006)
Evidence for the activation of 1α-hydroxyvitamin D2 by 25-hydroxyvitamin D-24-hydroxylase:: Delineation of pathways involving 1α,24-dihydroxyvitamin D2 and 1α,25-dihydroxyvitamin D2
S Masuda et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2006)
CYP27B1 null mice with LacZ reporter gene display no 25-hydroxyvitamin D3-1α-hydroxylase promoter activity in the skin
JL Vanhooke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1 alpha,25-dihydroxyvitamin D-3: Implications for drug-induced osteomalacia
Y Xu et al.
MOLECULAR PHARMACOLOGY (2006)
Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism
T Shimada et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues
GM Zinser et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
The Vitamin D endocrine system of the gut -: Its possible role in colorectal cancer prevention
HS Cross et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
Role of the vitamin D receptor in FGF23 action on phosphate metabolism
Y Inoue et al.
BIOCHEMICAL JOURNAL (2005)
Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development
YB Xue et al.
HUMAN MOLECULAR GENETICS (2005)
Altered pharmacokinetics of 1α,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 in the blood and tissues of the 25-hydroxyvitamin D-24-hydroxylase (Cyp24a1) null mouse
S Masuda et al.
ENDOCRINOLOGY (2005)
CYP3A4 is a vitamin D-24- and 25-hydroxylase: Analysis of structure function by site-directed mutagenesis
RP Gupta et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
1α-hydroxylase transactivation by γ-interferon in murine macrophages requires enhanced C/EBPβ expression and activation
L Esteban et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2004)
25 hydroxyvitamin D 1 α-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis
DD Bikle et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
CYP3A4 is a human microsomal vitamin D 25-hydroxylase
RP Gupta et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2004)
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis
T Shimada et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2004)
25-hydroxyvitamin D3-1α-hydroxylase expression in normal and malignant human colon
G Bises et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2004)
Enzymes involved in the activation and inactivation of vitamin D
DE Prosser et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
Transgenic mice expressing fibroblast growth factor 23 under the control of the α1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis
T Larsson et al.
ENDOCRINOLOGY (2004)
Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase
JB Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity
A Annalora et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
De-orphanization of cytochrome P450 2R1 - A microsomal vitamin D 25-hydroxylase
JB Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1)
O Dardenne et al.
BONE (2003)
Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3:: Biochemical, histomorphometric, and biomechanical analyses
O Dardenne et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2003)
The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency
XY Bai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Prostatic 25-hydroxyvitamin D-1α-hydroxylase and its implication in prostate cancer
TC Chen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Conventional and tissue-specific inactivation of the 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1)
R St-Arnaud et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Human fibroblast growth factor-23 mutants suppress Na+ -dependent phosphate co-transport activity and 1α,25-dihydroxyvitamin D3 production
H Saito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Comparison of P450s from human and fugu: 420 million years of vertebrate P450 evolution
DR Nelson
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements
PD Thompson et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Modulation of renal Ca2+ transport protein genes by dietary Ca2+ and 1,25-dihydroxyvitamin D3 in 25-hydroxyvitamin D3-1α-hydroxylase knockout mice
JGJ Hoenderop et al.
FASEB JOURNAL (2002)
25-Hydroxyvitamin D-1α-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer
LW Whitlatch et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2002)
Novel gene mutations in patients with 1α-hydroxylase deficiency that confer partial enzyme activity in vitro
XM Wang et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2002)
Transcriptional control of intestinal cytochrome P-4503A by 1α,25-dihydroxy vitamin D3
KE Thummel et al.
MOLECULAR PHARMACOLOGY (2001)
Parathyroid hormone regulates 25-hydroxyvitamin D3-24-hydroxylase mRNA by altering its stability
C Zierold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The molecular basis of vitamin D-dependent rickets type I
S Kitanaka et al.
ENDOCRINE JOURNAL (2001)
25-hydroxy-vitamin D metabolism in human colon cancer cells during tumor progression
P Bareis et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Targeted inactivation of the 25-hydroxyvitamin D3-1α-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets
O Dardenne et al.
ENDOCRINOLOGY (2001)
Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme:: Evidence for skeletal, reproductive, and immune dysfunction
DK Panda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
25-hydroxyvitamin D-1α-hydroxylase in normal and malignant colon tissue
V Tangpricha et al.
LANCET (2001)
Extrarenal expression of 25-hydroxyvitamin D3-1α-hydroxylase
D Zehnder et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia - Reversal by cholic acid feeding
JJ Repa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24
T Sakaki et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Vitamin D 1α-hydroxylase
WL Miller et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2000)
Regulation of the porcine 1,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 and parathyroid hormone in AOK-B50 cells
C Zierold et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Deficient mineralization of intramembranous bone in vitamin D-24-hydroxylase-ablated mice is due to elevated 1,25-dihydroxyvitamin D and not to the absence of 24,25-dihydroxyvitamin D
R St-Arnaud et al.
ENDOCRINOLOGY (2000)
Identification of a 25-hydroxyvitamin D3 1α-hydroxylase gene transcription product in cultures of human syncytiotrophoblast cells
L Díaz et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2000)
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
DG Albertson et al.
NATURE GENETICS (2000)
Case-control study of factors associated with nutritional rickets in Nigerian children
TD Thacher et al.
JOURNAL OF PEDIATRICS (2000)
分享论文
