4.6 Article

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Novel progesterone receptor modulators with gene selective and context-dependent partial agonism

Thomas J. Berrodin et al.

BIOCHEMICAL PHARMACOLOGY (2009)

Article Biochemistry & Molecular Biology

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

Adelheid Kratzer et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Chemistry, Medicinal

Carboxylic acid based quinolines as liver X receptor modulators that have LXR beta receptor binding selectivity

Balhua Hu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Review Cardiac & Cardiovascular Systems

Liver X Receptors (LXR) as Therapeutic Targets in Dyslipidemia

Jerzy Beltowski

CARDIOVASCULAR THERAPEUTICS (2008)

Review Chemistry, Medicinal

Recent advances in Liver X Receptor biology and chemistry

Bryan J. Goodwin et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)

Article Pharmacology & Pharmacy

Antiatherosclerotic Effects of a Novel Synthetic Tissue-Selective Steroidal Liver X Receptor Agonist in Low-Density Lipoprotein Receptor-Deficient Mice

Dacheng Peng et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Article Medicine, Research & Experimental

Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells

Elizabeth A. DiBlasio-Smith et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2008)

Review Hematology

Mouse models for atherosclerosis and pharmaceutical modifiers

Susanne Zadelaar et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Article Medicine, Research & Experimental

Ligand activation of LXRβ reverses atherosclerosis and cellular cholesterol overload in mice lacking LXRα and apoE

Michelle N. Bradley et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Medicine, Research & Experimental

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

LR Brunham et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Biochemistry & Molecular Biology

Synthetic LXR agonists increase LDL in CETP species

PHE Groot et al.

JOURNAL OF LIPID RESEARCH (2005)

Article Biochemistry & Molecular Biology

Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition

CA Argmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Regulation of complement C3 expression by the bile acid receptor FXR

JL Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Letter Hematology

Toll-like receptors, endocrine stress response, and arteriosclerosis

SR Bornstein et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor

EM Quinet et al.

JOURNAL OF LIPID RESEARCH (2004)

Article Medicine, General & Internal

Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes - A randomized controlled trial

SE Nissen et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)

Article Pharmacology & Pharmacy

LXRs: new therapeutic targets in atherosclerosis?

SB Joseph et al.

CURRENT OPINION IN PHARMACOLOGY (2003)

Article Multidisciplinary Sciences

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

RK Tangirala et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

SB Joseph et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β

JJ Repa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues

M Van Eck et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Cell Biology

Role of LXRs in control of lipogenesis

JR Schultz et al.

GENES & DEVELOPMENT (2000)

Article Chemistry, Medicinal

Identification of a chemical tool for the orphan nuclear receptor FXR

PR Maloney et al.

JOURNAL OF MEDICINAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

CD Yu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)