Adult cystic hygroma: successful use of OK-432 (Picibanil®)

Objective: We report an adult case of cystic lymphangioma treated with OK-432 (Picibanil (R)). Method: A case report and review of the literature concerning the use of OK-432 to treat cystic lymphangioma is presented. Results: A 31-year-old woman developed a cystic lymphangioma four weeks post-partum. This was treated initially by aspiration, for diagnostic purposes. Investigation suggested that surgery would be challenging. A review of the literature demonstrated success with OK-432 in the treatment of this condition, although primarily in the paediatric population. This patient was successfully treated thus, and at the time of writing remained symptom free. A suggested management plan is outlined. Conclusion: Treatment with OK-432 is useful in the management of cystic lymphangiomas in adults and should be considered as first line treatment.