'Click labelling' in PET radiochemistry

The copper(I)-catalysed 1,3-dipolar cylcoaddition of terminal alkynes with substituted azides has seen a rapidly growing popularity in a wide range of applications. This versatile coupling reaction has been also recognised as an invaluable tool to meet the high radiosynthetic demands of tracers for Positron Emission Tomography (PET). Here, we are reviewing publications from 2006 to March 2009.