期刊
OSTEOPOROSIS INTERNATIONAL
卷 27, 期 2, 页码 549-558出版社
SPRINGER LONDON LTD
DOI: 10.1007/s00198-015-3277-9
关键词
Burden; Cost; Epidemiology; Health economics; Hip fracture; Osteoporosis
资金
- AMGEN
- Merck
- Roche
- Q-Med
- Flexion
- Bioiberica
- Servier
- GSK
- Alliance for Better Bone Health
- MSD
- Eli Lilly
- Pfizer
- Novartis
- Medtronic
- Lilly UK
- Internis
- Consilient Health
- Jarrow Formulas
- MRC [MC_U147585819, MC_U147585827] Funding Source: UKRI
- Medical Research Council [MC_UU_12011/1, MC_U147585824, MC_U147585819, MC_UP_A620_1014, U1475000001, MC_U147585827] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0508-10082, 11/1023/01, NF-SI-0513-10085] Funding Source: researchfish
Using a large cohort of hip fracture patients, we estimated hospital costs to be 14,163 pound and 2139 pound in the first and second year following fracture, respectively. Second hip and non-hip fractures were major cost drivers. There is a strong economic incentive to identify cost-effective approaches for hip fracture prevention. Introduction The purpose of this study was to estimate hospital costs of hip fracture up to 2 years post-fracture and compare costs before and after the index fracture. Methods A cohort of patients aged over 60 years admitted with a hip fracture in a UK region between 2003 and 2013 were identified from hospital records and followed until death or administrative censoring. All hospital records were valued using 2012/2013 unit costs, and non-parametric censoring methods were used to adjust for censoring when estimating average annual costs. A generalised linear model examined the main predictors of hospital costs. Results A cohort of 33,152 patients with a hip fracture was identified (mean age 83 years (SD 8.2). The mean censor-adjusted 1- and 2-year hospital costs after index hip fracture were 14,163 pound (95 % confidence interval (CI) 14,008 pound to 14,317) pound and 16,302 pound (95 % CI 16,097 pound to 16,515) pound, respectively. Index admission accounted for 61 % (8613; pound 95 % CI 8565 pound to 8661) pound of total 1-year hospital costs which were 10,964 pound higher compared to the year pre-event (p < 0.001). The main predictors of 1-year hospital costs were second hip fracture, other non-hip fragility fractures requiring hospitalisation and hip fracture-related complications. Total UK annual hospital costs associated with incident hip fractures were estimated at 1.1 pound billion. Conclusions Hospital costs following hip fracture are high and mostly occur in the first year after the index hip fracture. Experiencing a second hip fracture after the index fracture accounted for much of the increase in costs. There is a strong economic incentive to prioritise research funds towards identifying the best approaches to prevent both index and subsequent hip fractures.
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