期刊
JOURNAL OF INFECTIOUS DISEASES
卷 202, 期 -, 页码 S289-S296出版社
OXFORD UNIV PRESS INC
DOI: 10.1086/655656
关键词
-
资金
- National Institutes of Health (NIH) [AI077473]
- National Institute of Allergy and Infectious Diseases, NIH
- Office of AIDS Research, National Institutes of Health
Individuals with recent human immunodeficiency virus type 1 (HIV-1) acquisition are likely to be a major source for other new infections because they have a high level of plasma virus, and the circulating virions possess unique properties that are highly suited for transmission. The acute infection period, however, presents a unique window of opportunity, because there are a limited number of genetic variants. Studies aim to elucidate the nature of the transmitted viruses and understand the mechanisms that inhibit the majority of variants present in the chronically infected partner from establishing a productive infection in the naive host. Greater understanding of these issues may open promising new ways to effectively block HIV-1 transmission.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据