期刊
JOURNAL OF INFECTION
卷 65, 期 5, 页码 400-405出版社
W B SAUNDERS CO LTD
DOI: 10.1016/j.jinf.2012.06.010
关键词
Staphylococcus aureus; MALDI-TOF MS; Isogenic; SCCmec; mecA
MALDI-TOF MS-based peak differences in oxacillin-resistant Staphylococcus aureus and oxacillin-susceptible S. aureus isolates have been described previously. Unfortunately, these isolates were not isogenic with respect to their mecA gene. Ours is the first to use a SCCmec-harboring parent and a SCCmec-lacking daughter strain, with the same genetic background, to unequivocally rule out strain-specific protein peaks. We could not show differences in the peak profiles within the preset Biotyper settings used for MALDI-TOF-based identification in this pair of SCCmec-harboring parent and SCCmec-lacking daughter strains. (c) 2012 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
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