相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mammalian cell protein expression for biopharmaceutical production
Jianwei Zhu
BIOTECHNOLOGY ADVANCES (2012)
Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing
Geisa A. L. Goncalves et al.
BIOTECHNOLOGY JOURNAL (2012)
Mammalian cells as biopharmaceutical production hosts in the age of omics
Stefanie Dietmair et al.
BIOTECHNOLOGY JOURNAL (2012)
High-throughput methods for miniaturization and automation of monoclonal antibody purification processes
Katrin Treier et al.
BIOTECHNOLOGY PROGRESS (2012)
Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae
Jin Hou et al.
FEMS YEAST RESEARCH (2012)
The need for innovation in biomanufacturing
Uwe Gottschalk et al.
NATURE BIOTECHNOLOGY (2012)
A Multi-Omics Analysis of Recombinant Protein Production in Hek293 Cells
Stefanie Dietmair et al.
PLOS ONE (2012)
Systems biotechnology of animal cells: the road to prediction
Nuno Carinhas et al.
TRENDS IN BIOTECHNOLOGY (2012)
Engineering of Therapeutic Proteins Production in Escherichia coli
Mariusz Kamionka
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2011)
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing
Jennifer Becker et al.
JOURNAL OF BIOTECHNOLOGY (2011)
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line
Xun Xu et al.
NATURE BIOTECHNOLOGY (2011)
'Pharmers' hope for first plant drug harvest
Alisa Opar
NATURE REVIEWS DRUG DISCOVERY (2011)
Enhanced protein secretion from multiprotease-deficient fission yeast by modification of its vacuolar protein sorting pathway
Alimjan Idiris et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Engineering of protein secretion in yeast: strategies and impact on protein production
Alimjan Idiris et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Disposable bioreactors: the current state-of-the-art and recommended applications in biotechnology
Regine Eibl et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Gene amplification and vector engineering to achieve rapid and high-level therapeutic protein production using the Dhfr-based CHO cell selection system
Jonathan J. Cacciatore et al.
BIOTECHNOLOGY ADVANCES (2010)
Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system
Hong Zhou et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Biopharmaceutical benchmarks 2010
Gary Walsh
NATURE BIOTECHNOLOGY (2010)
Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems
Matthias Funke et al.
MICROBIAL CELL FACTORIES (2010)
Application of microbioreactors in fermentation process development: a review
Daniel Schapper et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2009)
RNA interference technology to improve recombinant protein production in Chinese hamster ovary cells
Suh-Chin Wu
BIOTECHNOLOGY ADVANCES (2009)
The production of biopharmaceuticals in plant systems
Saskia R. Karg et al.
BIOTECHNOLOGY ADVANCES (2009)
Extracellular recombinant protein production from Escherichia coli
Ye Ni et al.
BIOTECHNOLOGY LETTERS (2009)
Optimal and consistent protein glycosylation in mammalian cell culture
Patrick Hossler et al.
GLYCOBIOLOGY (2009)
Design Parameters to Control Synthetic Gene Expression in Escherichia coli
Mark Welch et al.
PLOS ONE (2009)
Towards revealing the structure of bacterial inclusion bodies
Lei Wang
PRION (2009)
Modulation of Chaperone Gene Expression in Mutagenized Saccharomyces cerevisiae Strains Developed for Recombinant Human Albumin Production Results in Increased Production of Multiple Heterologous Proteins
T. Payne et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)
Sec- and Tat-mediated protein secretion across the bacterial cytoplasmic membrane -: Distinct translocases and mechanisms
Paolo Natale et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
Bacterial inclusion bodies contain amyloid-like structure
Lei Wang et al.
PLOS BIOLOGY (2008)
Glycosylation engineering in yeast: the advent of fully humanized yeast
Stephen R. Hamilton et al.
CURRENT OPINION IN BIOTECHNOLOGY (2007)
Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in Yeasts
Brigitte Gasser et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
Yeast mutant with efficient secretion identified by a novel secretory reporter, Cluc
Naoko Kanjou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives
Lucia Baldi et al.
BIOTECHNOLOGY LETTERS (2007)
The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide
Stian Knappskog et al.
JOURNAL OF BIOTECHNOLOGY (2007)
Engineering cell physiology to enhance recombinant protein production in Escherichia coli
C. Perry Chou
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2007)
Recombinant protein production in an Escherichia coli reduced genome strain
Shamik S. Sharma et al.
METABOLIC ENGINEERING (2007)
Advancing mammalian cell culture engineering using genome-scale technologies
Timothy J. Griffin et al.
TRENDS IN BIOTECHNOLOGY (2007)
Selection methods for high-producing mammalian cell lines
Susan M. Browne et al.
TRENDS IN BIOTECHNOLOGY (2007)
Microscalle bioprocess optimisation
Martina Micheletti et al.
CURRENT OPINION IN BIOTECHNOLOGY (2006)
Post-translational modifications in the context of therapeutic proteins
Gary Walsh et al.
NATURE BIOTECHNOLOGY (2006)
Humanization of yeast to produce complex terminally sialylated glycoproteins
Stephen R. Hamilton et al.
SCIENCE (2006)
Global gene expression in Escherichia coli K-12 during short-term and long-term adaptation to glucose-limited continuous culture conditions
Alessandro G. Franchini et al.
MICROBIOLOGY-SGM (2006)
Emergent properties of reduced-genome Escherichia coli
G Pósfai et al.
SCIENCE (2006)
Proteomic analysis of extracellular proteins from Escherichia coli W3110
MP Nandakumar et al.
JOURNAL OF PROTEOME RESEARCH (2006)
Modulation of therapeutic antibody effector functions by glycosylation engineering:: Influence of Golgi enzyme localization domain and co-expression of heterologous β1,4-N-acetylglucosaminyltransferase III and Golgi α-mannosidase II
C Ferrara et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Applications of cell sorting in biotechnology
D Mattanovich et al.
MICROBIAL CELL FACTORIES (2006)
Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells
THJ Kwaks et al.
TRENDS IN BIOTECHNOLOGY (2006)
Initial transcriptome and proteome analyses of low culture temperature-induced expression in CHO cells producing erythropoietin
JY Baik et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
A support vector machine-based method for predicting the propensity of a protein to be soluble or to form inclusion body on overexpression in Escherichia coli
S Idicula-Thomas et al.
BIOINFORMATICS (2006)
Production of recombinant proteins by high cell density culture of Escherichia coli
JH Choi et al.
CHEMICAL ENGINEERING SCIENCE (2006)
Extracellular accumulation of recombinant proteins fused to the carrier protein YebF in Escherichia coli
GJ Zhang et al.
NATURE BIOTECHNOLOGY (2006)
Automated in situ measurement of cell-specific antibody secretion and laser-mediated purification for rapid cloning of highly-secreting producers
EG Hanania et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals
M Butler
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)
Large-scale gene expression analysis of cholesterol dependence in NSO cells
G Seth et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
被撤回的出版物: Strategies for efficient production of heterologous proteins in Escherichia coli (Retracted article. See vol. 98, pg. 5787, 2014)
S Jana et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)
Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli
FT Haddadin et al.
BIOTECHNOLOGY AND BIOENGINEERING (2005)
Solubilization and refolding of bacterial inclusion body proteins
SM Singh et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2005)
The key to development: interpreting the histone code?
R Margueron et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
Proteomic profiling of recombinant Escherichia coli in high-cell-density fermentations for improved production of an antibody fragment biopharmaceutical
IS Aldor et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)
Heterologous protein production using the Pichia pastoris expression system
S Macauley-Patrick et al.
YEAST (2005)
Understanding the relationship between the primary structure of proteins and its propensity to be soluble on overexpression in Escherichia coli
S Idicula-Thomas et al.
PROTEIN SCIENCE (2005)
Advanced genetic strategies for recombinant protein expression in Escherichia coli
HP Sorensen et al.
JOURNAL OF BIOTECHNOLOGY (2005)
Targeting of a histone acetyltransferase domain to a promoter enhances protein expression levels in mammalian cells
T Kwaks et al.
JOURNAL OF BIOTECHNOLOGY (2005)
Protein disulfide isomerase, but not binding protein, overexpression enhances secretion of a non-disulfide-bonded protein in yeast
JD Smith et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Viral preprotoxin signal sequence allows efficient secretion of green fluorescent protein by candida glabrata, Pichia pastoris, Saccharomyces cerevisiae, and Schizosaccharomyces pombe
A Eiden-Plach et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Large scale gene expression profiling of metabolic shift of mammalian cells in culture
R Korke et al.
JOURNAL OF BIOTECHNOLOGY (2004)
Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris:: production of complex humanized glycoproteins with terminal galactose
P Bobrowicz et al.
GLYCOBIOLOGY (2004)
Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae
L Jonson et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Constitutive production of human leptin by fed-batch culture of recombinant rpoS- Escherichia coli
KJ Jeong et al.
PROTEIN EXPRESSION AND PURIFICATION (2004)
Production of recombinant protein therapeutics in cultivated mammalian cells
FM Wurm
NATURE BIOTECHNOLOGY (2004)
Recombinant protein folding and misfolding in Escherichia coli
F Baneyx et al.
NATURE BIOTECHNOLOGY (2004)
Advances in the production of human therapeutic proteins in yeasts and filamentous fungi
TU Gerngross
NATURE BIOTECHNOLOGY (2004)
High-throughput expression of C-elegans proteins
CH Luan et al.
GENOME RESEARCH (2004)
Effect of low culture temperature on specific productivity and transcription level of anti-4-1BB antibody in recombinant Chinese hamster ovary cells
SK Yoon et al.
BIOTECHNOLOGY PROGRESS (2003)
Engineering Escherichia coli for increased productivity of serine-rich proteins based on proteome profiling
MJ Han et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures
B Figueroa et al.
METABOLIC ENGINEERING (2003)
Production of complex human glycoproteins in yeast
SR Hamilton et al.
SCIENCE (2003)
Enhanced production of insulin-like growth factor I fusion protein in Escherichia coli by coexpression of the down-regulated genes identified by transcriptome profiling
JH Choi et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Over-expression of Escherichia coli F1Fo-ATPase subunit a is inhibited by instability of the uncB gene transcript
I Arechaga et al.
FEBS LETTERS (2003)
A simple method for enriching populations of transfected CHO cells for cells of higher specific productivity
SCG Brezinsky et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2003)
Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris
BK Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Identification of cellular changes associated with increased production of human growth hormone in a recombinant Chinese hamster ovary cell line
DD Van Dyk et al.
PROTEOMICS (2003)
Enhanced production of recombinant proteins in Escherichia coli by filamentation suppression
KJ Jeong et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Proteome analysis of antibody-expressing CHO cells in response to hyperosmotic pressure
MS Lee et al.
BIOTECHNOLOGY PROGRESS (2003)
Construction of engineered CHO strains for high-level production of recombinant proteins
M Kito et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2002)
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E-coli
M Wacker et al.
SCIENCE (2002)
Structural requirements of the mRNA for intracistronic translation initiation of the enterobacterial infB gene
BS Laursen et al.
GENES TO CELLS (2002)
Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris
GPL Cereghino et al.
CURRENT OPINION IN BIOTECHNOLOGY (2002)
Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3
NS Kim et al.
BIOTECHNOLOGY AND BIOENGINEERING (2002)
Protein folding - Molecular chaperones in the cytosol: from nascent chain to folded protein
FU Hartl et al.
SCIENCE (2002)
Overproduction of BiP negatively affects the secretion of Aspergillus niger glucose oxidase by the yeast Hansenula polymorpha
M van der Heide et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2002)
Blocking of acidosis-mediated apoptosis by a reduction of lactate dehydrogenase activity through antisense mRNA expression
DW Jeong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Chromosomal editing in Escherichia coli -: Vectors for DNA integration and excision
P Balbás et al.
MOLECULAR BIOTECHNOLOGY (2001)
Expression of GnTIII in a recombinant anti-CD20 CHO production cell line:: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FcγRIII
J Davies et al.
BIOTECHNOLOGY AND BIOENGINEERING (2001)
Intracellular retention of newly synthesized insulin in yeast is caused by endoproteolytic processing in the golgi complex
BY Zhang et al.
JOURNAL OF CELL BIOLOGY (2001)
Roles of thiol-redox pathways in bacteria
D Ritz et al.
ANNUAL REVIEW OF MICROBIOLOGY (2001)
Growth of NS0 cells in protein-free, chemically defined medium
S Gorfien et al.
BIOTECHNOLOGY PROGRESS (2000)
tRNA-assisted overproduction of eukaryotic ribosomal proteins
G Dieci et al.
PROTEIN EXPRESSION AND PURIFICATION (2000)
Green fluorescent protein as a second selectable marker for selection of high producing clones from transfected CHO cells
YG Meng et al.
GENE (2000)
Heterologous protein expression in the methylotrophic yeast Pichia pastoris
JL Cereghino et al.
FEMS MICROBIOLOGY REVIEWS (2000)