期刊
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
卷 15, 期 5, 页码 758-762出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jiec.2009.09.059
关键词
Pluronic F127; Ethyl cellulose; Poly(epsilon-caprolacton); Double emulsion; Temperature-dependent release
资金
- Ministry of Marine Affairs & Fisheries, Republic of Korea [20060024]
Microcapsules encapsulating Pluronic F127 were prepared by a double emulsion technique. Poly(epsilon-caprolacton) (PCL) and ethyl cellulose (EC) were used as wall materials of microcapsule. When primary water-in-oil (W/O) emulsions were prepared, Pluronic F127 solution in distilled water (20%) was used as a water phase, and PCL/EC solution in dichloromethane (5%) as an oil phase. The ratio of water to oil phase, 1:12, and the ratio of PCL to EC, 1.7:3.3, led to microcapsules having smooth surfaces. Temperature-dependent releases from the microcapsules were investigated for 6 h using fluorescein isothiocyanate-dextran and blue-dextran as dyes. The degrees of release were higher at higher temperatures. The promoted release at a higher temperature is thought be due to an enhanced diffusion of the dyes, but not due to the thermo-sensitive property of Pluronic F127. (C) 2009 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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