期刊
ORGANIC LETTERS
卷 17, 期 16, 页码 4094-4097出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b02038
关键词
-
资金
- National Basic Research Program of China [2015CB856600]
- NSFC [21422206, 21272206]
- Fundamental Research Funds for the Central Universities
- Zhejiang Provincial NSFC [LZ12B02001]
A cobalt(III)-catalyzed C-2 selective C-H alkynylation of indoles using hypervalent iodine-alkyne reagents is described. A broad range of synthetically useful functional groups (-F, -Cl, -Br, -CO2Me, -CN) were tolerated, providing an efficient and robust protocol for the synthesis of C-2 alkynylated indoles. The pyrimidyl and silyl protecting groups could be easily removed to give the corresponding 2-ethynyl-1H-indole.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据