期刊
ORGANIC LETTERS
卷 17, 期 13, 页码 3240-3243出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01387
关键词
-
资金
- National Cancer Institute, NIH [R37 CA044848]
Chemical investigation of a marine actinomycete within the family Streptomycetaceae (our strain CNQ-149) has led to the isolation of the unprecedented alkaloids, actinobenzoquinoline (1) and actinophenanthrolines A-C (2-4). The chemical structures of 1-4 were assigned by interpretation of NMR spectroscopic data, and their absolute configurations were assigned by X-ray analysis. Actinobenzoquinoline possesses a 5-methyloxazolidin-4-one moiety and a dihydrobento[h],quinoline core structure, while actinophenanthrolines A-C are composed of hydroxypropanamide-substituted 1,7-phenanthroline core skeletons.
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