期刊
JOURNAL OF IMMUNOLOGICAL METHODS
卷 410, 期 -, 页码 100-112出版社
ELSEVIER
DOI: 10.1016/j.jim.2014.03.022
关键词
Fungus; Animal model; Mouse; Immune response; Pathogenesis; Yeast
资金
- Robert Sinskey Foundation
- NIH [RO1 AI093808, R21 AI105617]
Fungi represent emerging infectious threats to human populations worldwide. Mice and other laboratory animals have proved invaluable in modeling clinical syndromes associated with superficial and life-threatening invasive mycoses. This review outlines salient features of common vertebrate animal model systems to study fungal pathogenesis, host antifungal immune responses, and antifungal compounds. (C) 2014 Elsevier B.V. All rights reserved.
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