期刊
ORGANIC LETTERS
卷 17, 期 15, 页码 3790-3793出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01733
关键词
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资金
- NSF of China [21202048]
- Program for Minjiang Scholar [10BS216]
- Xiamen Southern Oceanographic Center [13GYY003NF16]
- NSF of Fujian Province, China [2013J01050]
- Promotion Program for Young and Middle-aged Teacher in Science and Technology Research of Huaqiao University [ZQN-PY120]
N-Pyridylation of various N-heteroarenes, including N-heteroarene-containing peptides, was achieved using N-propargyl enaminones (isolated or generated in situ from propargyl amine and propynones) as masked polysubstituted pyridine cores. This metal-free procedure proceeds under mild reaction conditions and generates 1 equiv of H2O as the sole byproduct
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