期刊
ORGANIC LETTERS
卷 17, 期 3, 页码 652-655出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol5036722
关键词
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资金
- Ministry of Education, Culture, Sports, Science and Technology of Japan [24310160, 20436992]
- Shimadzu Science Foundation
- Novartis Foundation (Japan) for the Promotion of Science
- Uehara Memorial Foundation
- Keio Gijuku Fukuzawa Memorial Fund for the Advancement of Education and Research
- Grants-in-Aid for Scientific Research [15H06584, 25750386] Funding Source: KAKEN
An acetylene-containing lipopeptide, jahanyne, was isolated from the marine cyanobacterium Lyngbya sp. Its gross structure was established by spectroscopic analyses, and the absolute configuration was clarified based on a combination of chiral HPLC analyses, spectroscopic analyses, and derivatization reactions. Jahanyne significantly inhibited the growth of human cancer cells and induced apoptosis in HeLa cells.
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