期刊
ORGANIC LETTERS
卷 17, 期 6, 页码 1361-1364出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00005
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资金
- National Basic Research Program of China (973 program) [2013CB911104]
- National Natural Science Foundation of China [21202087]
- Tianjin Science and Technology Program [13JCYBJC24300, 13JCQNJC13100]
- Ministry of Education of China [B06005]
A direct aldol reaction employing 2,4-thiazolidinediones as nucleophilic donors was performed to modify peptides and protein under mild conditions. Various functional groups could be readily introduced into protein without conformation change.
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