4.8 Article

Construction of Seven-Membered Carbocycles via Cyclopropanols

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ORGANIC LETTERS
卷 17, 期 23, 页码 5820-5823

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AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b02978

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  1. NSF [CHE-1265843]
  2. Division Of Chemistry
  3. Direct For Mathematical & Physical Scien [1265843] Funding Source: National Science Foundation

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A new method for seven-membered ring annulation has been devised by an intramolecular cross-coupling of cyclopropanols and aryl/alkenyl halides. This cyclization reaction is broad in scope and provides easy access to not only fused but also bridged bicyclic compounds.

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