期刊
ORGANIC LETTERS
卷 17, 期 15, 页码 3930-3933出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b02014
关键词
-
资金
- Russian Scientific Fund [14-50-00069]
Significant expansion of heterocyclic product space accessible by the Castagnoli-Cushman reaction (CCR) has been achieved via the use of glutaric anhydride analogues containing endocyclic substitutions with oxygen, nitrogen, and sulfur. Incorporation of these heteroatoms in the anhydrides backbone results in enhanced reactivity and generally lower temperatures that are required for the reactions to go to completion. These findings are particularly significant in light of the CCR recently recognized as an efficient tool for lead-oriented synthesis.
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