期刊
JOURNAL OF HYPERTENSION
卷 27, 期 10, 页码 2051-2054出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/HJH.0b013e328330052a
关键词
adolescence; blood pressure; offspring; preeclampsia
资金
- National Cancer Institute of the United States
- Stavanger University Hospital, Norway
Objective To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. Method SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies. The association of preeclampsia with later BP was adjusted for perinatal information, anthropometric factors at follow-up, and maternal BP and BMI. Results In the preeclampsia group, SBP in early adolescence was higher than in the normotensive group (115.3 vs. 113.5mmHg, P=0.03), but there was no difference in DBP (66.4 vs. 65.3mmHg, P=0.10). After adjustment for maternal body mass and BP, the difference in SBP was largely attenuated. Conclusion The higher SBP among adolescent offspring of preeclamptic pregnancies could be mediated by maternal body mass or BP, factors that are positively associated with the risk of preeclampsia in pregnancy. J Hypertens 27: 2051-2054 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
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