期刊
ORGANIC LETTERS
卷 17, 期 20, 页码 5080-5083出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b02593
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资金
- China Scholarship Council (CSC)
The reversible formation of covalent bonds enabled by the remarkably high Lewis acidity of our calcium-based catalyst system was used for the development of a new type of multicomponent reaction. Accordingly, a pharmacologically interesting bicyclic amine was amplified from a highly efficient dynamic equilibrium. The product is formed with full diastereoselectivity, and as typical for our calcium-catalyzed reactions, precautions for the exclusion of air and moisture are unnecessary.
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