期刊
ORGANIC LETTERS
卷 17, 期 3, 页码 450-453出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol5034354
关键词
-
资金
- CAU
- Mid-Career Researcher Program at SNU [NRF-2013R1A2A1A01015998]
The soft a-vinyl enolization of (E)-beta-chlorovinyl ketones was investigated in the presence of various halogen electrophiles. Depending on the nature of halogen electrophiles, the selective formation of three products, namely alpha,alpha-dichloropropargyl ketones, alpha,gamma-dihaloallenyl ketones, and 3-halofurans, was observed. The observed regiodivergent nucleophilic pathways of (E)-beta-chlorovinyl ketones demonstrate the diversity-oriented synthesis strategy in which the nucleophilic reactivity of (E)-beta-chlorovinyl ketones can be selectively modulated by the choice of suitable hard and soft electrophiles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据