期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 13, 期 47, 页码 11432-11437出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob01258a
关键词
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An efficient copper-catalyzed cross-coupling reaction of biguanide hydrochloride derivatives with both aryl iodides and bromides under mild conditions has been developed. The reaction occurred in good yields and tolerated aryl halides containing functionalities such as nitriles, sulfonamides, ethers, and halogens. Alkyl and cyclic substituted biguanidines were also well tolerated.
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