期刊
JOURNAL OF HUMAN HYPERTENSION
卷 22, 期 7, 页码 512-515出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/jhh.2008.23
关键词
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资金
- NHLBI NIH HHS [N01HC25195, T32 HL069770, N01-HC-25195, P01 HL077378-05, P01 HL077378, HL069770, T32 HL069770-05, HL077378] Funding Source: Medline
Genetic polymorphisms that influence smooth muscle cell contraction and relaxation may affect the response to anti-hypertensive therapy. Our finding of lower blood pressure in the setting of treatment for hypertension, particularly with beta-blockade, in Caucasian KCNMB1-E65K carriers in two community cohorts has implications for personalization of therapy in hypertension.
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