期刊
JOURNAL OF HETEROCYCLIC CHEMISTRY
卷 51, 期 5, 页码 1282-1286出版社
WILEY
DOI: 10.1002/jhet.1682
关键词
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资金
- National Nature Science Foundation of China [20972121, 20872116]
- Science Foundation of Ministry of Education for the New Teacher at the University of China [20090141120058]
- Open Research Fund Program of the State Key Laboratory of Virology of China [2011002]
A one-step synthetic protocol for phthalazine derivatives has been developed. In the presence of Et3N, a series of phthalazine derivatives were conveniently prepared in high yield by the reaction of ortho-alkynylphenyl ketones and hydrazine under mild reaction conditions. The structure was unambiguously confirmed by X-ray crystallographic analysis of product 2i.
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