期刊
JOURNAL OF HETEROCYCLIC CHEMISTRY
卷 47, 期 3, 页码 611-615出版社
WILEY-BLACKWELL
DOI: 10.1002/jhet.366
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资金
- University of Tehran
A simple diastereoselective route to nicotine derivatives is presented. The one-pot three component 1,3-dipolar cycloaddition reaction of the Knoevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived in situ from pyridine-3-carbaldehyde and sarcosine give access to nicotine derivatives in good yields.
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