4.8 Article

EASL Clinical Practice Guidelines on nutrition in chronic liver disease

期刊

JOURNAL OF HEPATOLOGY
卷 70, 期 1, 页码 172-193

出版社

ELSEVIER
DOI: 10.1016/j.jhep.2018.06.024

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资金

  1. NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R21AR071046] Funding Source: NIH RePORTER
  2. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [U01DK061732, R01DK113196] Funding Source: NIH RePORTER
  3. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM119174] Funding Source: NIH RePORTER
  4. NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM [U01AA026976, P50AA024333, U01AA021893, P50AA024337, U01AA021890] Funding Source: NIH RePORTER

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A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease. These Clinical Practice Guidelines review the present knowledge in the field of nutrition in chronic liver disease and promote further research on this topic. Screening, assessment and principles of nutritional management are examined, with recommendations provided in specific settings such as hepatic encephalopathy, cirrhotic patients with bone disease, patients undergoing liver surgery or transplantation and critically ill cirrhotic patients. (C) 2018 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

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