期刊
JOURNAL OF HEART AND LUNG TRANSPLANTATION
卷 29, 期 7, 页码 811-813出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.healun.2010.02.005
关键词
pulmonary arterial hypertension; mechanical circulatory support; right ventricular failure; ECMO; pulmonary hypertension
资金
- Actelion Pharmaceuticals
- Gilead Sciences
- Pfizer
- United Therapeutics
We report the case of a treatment-naive patient with pulmonary arterial hypertension who presented with decompensated right ventricular failure and cardiogenic shock. Unstable hemodynamics, hypoxia and end-organ hypoperfusion limited up-titration of pharmacotherapy. Mechanical circulatory support with veno-venous extracorporeal membrane oxygenation (VV-ECMO) was initiated to permit dose titration of pulmonary vasodilator therapy. VV-ECMO was weaned after 10 days of support, with successful transition to intravenous epoprostenol and oral sildenafil. J Heart Lung Transplant 2010;29:811-3 (C) 2010 International Society for Heart and Lung Transplantation. All rights reserved.
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