期刊
JOURNAL OF HAZARDOUS MATERIALS
卷 260, 期 -, 页码 47-52出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jhazmat.2013.04.041
关键词
Nanofibers; Scanning electron microscopy; Digestive gland epithelial cells; Digestive system; Porcellio scaber
资金
- Ministry of High Education and Technology of Republic of Slovenia [P2-0050]
- Slovenian Research Agency [J1-4109, J2-4326, J3-4108, J4-3609, P1-0184]
- 7th FP EU Project NANOVALID [263147]
We provide data obtained by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) on the interaction of ingested tungsten nanofibers with epithelial cells of the digestive tubes of a test organism Porcellio scaber. Conventional toxicity endpoints including feeding behaviour, weight loss and mortality were also measured in each investigated animal. No toxicity was detected in any of exposed animals after 14 days of feeding on tungsten nanofiber dosed food, but when nanofibers enter the digestive system they can react with epithelial cells of the digestive tubes, becoming physically inserted into the cells. In this way, nanofibers can injure the epithelial cells of digestive gland tubes when they are ingested with food. Our SEM data suggest that peristaltic forces may have an important role, not predicted by in vitro experiments, in the interactions of nanomaterials with digestive intestinal cells. (C) 2013 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据