Recent progress in transition-metal-catalyzed trifluoromethylation of olefins using electrophilic CF3 reagents

For the past few years, transition-metal-catalyzed trifluoromethylation of olefins has been rapidly developing and has provided various types of organofluorine compounds containing a C(sp(3))-CF3 bond. In this review, we will concisely summarize recent development of trifluoromethylation of C=C bonds effected by a combination of transition metal catalysis and electrophilic trifluoromethylating reagents, such as Umemoto's and Togni's reagents. (C) 2014 Elsevier B.V. All rights reserved.