期刊
JOURNAL OF FLUORINE CHEMISTRY
卷 157, 期 -, 页码 58-62出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2013.11.007
关键词
Enaminones; Fluoroalkoxy group; Pyrazoles; Isoxazoles; Pyrimidines
2-Fluoroalkoxyenaminones were synthesized from alpha-fluoroalkoxyacetophenones and dimethylformamide dimethylacetal in almost quantitative yields. These compounds are promising aliphatic precursors for fluoroalkoxy containing heterocycles construction that was proved by reactions with hydrazine, hydroxylamine and amidines yielding corresponding pyrazoles, isoxazoles and pyrimidines. (C) 2013 Elsevier B.V. All rights reserved.
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