期刊
JOURNAL OF FLUORINE CHEMISTRY
卷 141, 期 -, 页码 11-15出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2012.05.014
关键词
Fluorinated solvent; Malononitrile; Resorcinol; Metal-free
资金
- Islamic Azad University, Ayatollah Amoli Branch
A highly efficient one-pot three-component regioselective synthesis of 2-amino-3-cyano-4H-chromene and tetrahydrobenzo[b]pyran derivatives has been developed by annulation of aldehydes, malononitrile, and resorcinol or dimedone under reflux conditions in 22,2-trifluoroethanol without the use of a catalyst or any other additive. (c) 2012 Elsevier B.V. All rights reserved.
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