期刊
OPHTHALMIC RESEARCH
卷 54, 期 3, 页码 124-127出版社
KARGER
DOI: 10.1159/000438758
关键词
Uveitis; Juvenile idiopathic arthritis; Biological agents
资金
- Australian Research Council [FT130101648]
Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients with this condition, systemic immunosuppressive therapy is frequently employed. The medical options for the treatment of JIA-associated uveitis have recently expanded beyond conventional innmunosuppressive drugs to the biological agents. The biological drugs that are most commonly employed for JIA-associated uveitis are the tumor necrosis factor-a inhibitors. Other biological agents that have been used to treat the disease include drugs that target cytokine receptors, lymphocyte antigens and lymphocyte co-stimulation signals. This Mini Review highlights recent developments in the medical treatment of JIA-associated uveitis. (C) 2015 S. Karger AG, Basel
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