期刊
JOURNAL OF FLUORINE CHEMISTRY
卷 138, 期 -, 页码 42-47出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2012.03.012
关键词
alpha-(Trifluoroethylidene)nitroethane; 1,3-Dicarbonyls; Primary amines; Three-component reaction; Grob cyclization; alpha-(Trifluoromethyl)pyrroles
资金
- Russian Foundation for Basic Research [11-03-00126-a]
A variety of substituted beta-(trifluoromethyl)pyrroles were easily synthesized in good yields by a one-pot, three-component Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonyls (ethyl acetoacetate, acetylacetone, benzoylacetone) and ammonia or primary aliphatic amines. (C) 2012 Elsevier B.V. All rights reserved.
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