期刊
JOURNAL OF FLUORESCENCE
卷 24, 期 1, 页码 1-5出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10895-013-1296-5
关键词
Hydrogen sulfide; Gasotransmitter; Fluorescent probe; Azide; Redox sensing
资金
- Chinese Scholarship Council
- Molecular Basis of Disease for a fellowship
- Center for Diagnostics and Therapeutics for a CDT/University fellowship
A second-generation sulfonyl azide-based fluorescent probe, 2,6-DNS-Az, has been developed for the quantitative detection of H2S in aqueous media such as phosphate buffer and bovine serum. Compare to the first-generation 1,5-DNS-Az probe, this probe shows both high sensitivity in phosphate buffer without the need for addition of surfactant and selectivity for sulfide over other anions and biomolecules, and thus can be used as a useful tool for detection of H2S in the biological system.
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