Synthesis and Chiral Recognition Properties of Novel Fluorescent Chemosensors for Amino Acid

The charge neutral chiral optical sensors 1a similar to d containing thiourea and amide groups were synthesized by simple steps in good yields and their structures were characterized by IR, H-1 NMR, C-13 NMR, MS spectra and elemental analysis. The enantioselective recognition for alpha-phenylglycine and phenylglycinol was examined by fluorescence emission and UV-vis spectra. The fluorescence and UV-vis spectra changes of 1a were obvious when the enantiomers of alpha-phenylglycine anion were added, which exhibited that 1a has good enantioselective recognition ability towards alpha-phenylglycine.