期刊
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
卷 24, 期 2, 页码 121-126出版社
SPRINGERNATURE
DOI: 10.1038/jes.2013.77
关键词
arsenic; bioaccumulation; keratin; nails; Rift Valley; water quality
资金
- Duke Global Health Institute
- Nicholas School of Environment
- Problem-Focused Interdisciplinary Research-Scholarship Teams (PFIRST) program at Duke University
Arsenic (As) contamination of drinking water is a worldwide phenomenon whose effect among vulnerable and rural communities in the Rift Valley of Ethiopia in eastern Africa is not well studied. This study examines As exposure and bioaccumulation from drinking water by monitoring human keratin in the form of toenails from exposed populations. Groundwater samples from drinking water wells (n = 34) were collected along with toenail samples (n = 58) from local communities and were analyzed for trace metals including As by inductively coupled plasma mass spectrometry (ICP-M5). Of the total number of wells tested, 53% had As level above the WHO maximum contamination level of 10 p.p.b. Arsenic in toenails was significantly correlated to corresponding drinking water (r=0.72; R-2=0.52; P < 0.001). This correlation improves for drinking water with As concentrations above 2 p.p.b. (r=0.74; R-2=0.54; P < 0.001). Male minors (< 18 years old) were found to have greater nail-As concentrations compared with adults consuming equal amounts of As (P < 0.05). Estimated As dose specifically from drinking water sources was also associated with nail concentrations (P < 0.01). We suggest that As measurement in nails could be a reliable method for detecting As exposure in residents living in rural areas.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据