期刊
JOURNAL OF EXPERIMENTAL MEDICINE
卷 207, 期 12, 页码 2537-2541出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1084/jem.20102260
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资金
- Howard Hughes Medical Institute Funding Source: Medline
- NHLBI NIH HHS [R01 HL032259] Funding Source: Medline
A relatively small cadre of lineage-restricted transcription factors largely orchestrates erythropoiesis, but how these nuclear factors interact to regulate this complex biology is still largely unknown. However, recent technological advances, such as chromatin immunoprecipitation (ChIP) paired with massively parallel sequencing (ChIP-seq), gene expression profiling, and comprehensive bioinformatic analyses, offer new insights into the intricacies of red cell molecular circuits.
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