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Bo Zhu et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
The Anti-proliferative Function of the TGF-β1 Signaling Pathway Involves the Repression of the Oncogenic TBX2 by Its Homologue TBX3
Jarod Li et al.
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Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors
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CANCER DISCOVERY (2014)
Dual Blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) Pathways Synergistically Inhibits Rhabdomyosarcoma Cell Growth In Vitro and In Vivo
Jane Renshaw et al.
CLINICAL CANCER RESEARCH (2013)
The T-box Transcription Factors TBX2 and TBX3 in Mammary Gland Development and Breast Cancer
Nataki C. Douglas et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2013)
The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion
Jade Peres et al.
MOLECULAR CANCER (2013)
TBX2 expression is regulated by PAX3 in the melanocyte lineage
Fang Liu et al.
PIGMENT CELL & MELANOMA RESEARCH (2013)
Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma
Durmus Burgucu et al.
BMC CANCER (2012)
Gamma Interferon Modulates Myogenesis through the Major Histocompatibility Complex Class II Transactivator, CIITA
Priya Londhe et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Sequential association of myogenic regulatory factors and E proteins at muscle-specific genes
Priya Londhe et al.
SKELETAL MUSCLE (2011)
Impaired Wnt Signaling in Embryonal Rhabdomyosarcoma Cells from p53/c-fos Double Mutant Mice
Shalini Singh et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
MicroRNA miR-183 Functions as an Oncogene by Targeting the Transcription Factor EGR1 and Promoting Tumor Cell Migration
Aaron L. Sarver et al.
CANCER RESEARCH (2010)
T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells
K. L. Redmond et al.
ONCOGENE (2010)
Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma
Robert C. Castellino et al.
PLOS ONE (2010)
PTEN and the PI3-Kinase Pathway in Cancer
Nader Chalhoub et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2009)
Phosphorylation keeps PTEN phosphatase closed for business
Alonzo H. Ross et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Tbx3 represses E-cadherin expression and enhances melanoma invasiveness
Mercedes Rodriguez et al.
CANCER RESEARCH (2008)
Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse:: roles of osteopontin
Jinyi Shao et al.
CARCINOGENESIS (2007)
Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: Distinct roles for Ship2 and PTEN
Adel Mandl et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
PAX3 and PAX3-FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN
Hong Gui Li et al.
CANCER LETTERS (2007)
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH
G. Joensson et al.
ONCOGENE (2007)
GSK3β mediates suppression of cyclin D2 expression by tumor suppressor PTEN
W. Huang et al.
ONCOGENE (2007)
Essential role for nuclear PTEN in maintaining chromosomal integrity
Wen Hong Shen et al.
CELL (2007)
Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer
Heidi Lyng et al.
BMC GENOMICS (2006)
Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients
M Lomnytska et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
p21WAF1 Expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells
Carmela Ciccarelli et al.
MOLECULAR CANCER (2005)
Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis
JH Chung et al.
CANCER RESEARCH (2005)
Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
KW Vance et al.
CANCER RESEARCH (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
Muscle-specific Pten deletion protects against insulin resistance and diabetes
N Wijesekara et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
PTEN expression elicited by EGR-1 transcription factor in calyculin a-induced apoptotic cells
H Okamura et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis
M Rowley et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2004)
Tbx2 directly represses the expression of the p21WAF1 cyclin-dependent kinase inhibitor
S Prince et al.
CANCER RESEARCH (2004)
TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines
WW Fan et al.
CANCER RESEARCH (2004)
Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells
XL Wan et al.
ONCOGENE (2003)
PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1
A Radu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo
F Relaix et al.
GENES & DEVELOPMENT (2003)
Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer
EH Mahlamäki et al.
GENES CHROMOSOMES & CANCER (2002)
PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway
LP Weng et al.
HUMAN MOLECULAR GENETICS (2002)
Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation
H Carlson et al.
ONCOGENE (2002)
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
T Virolle et al.
NATURE CELL BIOLOGY (2001)
PTEN coordinates G1 arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model
LP Weng et al.
HUMAN MOLECULAR GENETICS (2001)
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse
A Di Cristofano et al.
NATURE GENETICS (2001)
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers
JJL Jacobs et al.
NATURE GENETICS (2000)
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
A Toker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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