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Min H. Kang et al.
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Yunbo Wei et al.
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Sonia Lain et al.
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E. C. LaCasse et al.
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Sanjeev Shangary et al.
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Frank M. Boeckler et al.
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Markus Jensen et al.
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Domagoj Vucic et al.
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Cell death modalities: classification and pathophysiological implications
L. Galluzzi et al.
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Rita Bayer Lopes et al.
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Faina Vikhanskaya et al.
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Mitochondrial membrane permeabilization in cell death
Guido Kroemer et al.
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Johannes H. Bauer et al.
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Ken Ohnishi et al.
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Caspase activity is downregulated in choriocarcinoma: a cDNA array differential expression study
PY Fong et al.
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Caspases: pharmacological manipulation of cell death
IN Lavrik et al.
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Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer
M Ocker et al.
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Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells
K Kami et al.
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Antisense-mediated downregulation of anti-apoptotic proteins induces apoptosis and sensitizes head and neck squamous cell carcinoma cells to chemotherapy
H Sharma et al.
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An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T Oltersdorf et al.
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Targeting apoptosis pathways in cancer therapy
IM Ghobrial et al.
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Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
SL Fink et al.
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Gene transfer of constitutively active caspase-3 induces apoptosis in a human hepatoma cell line
L Cam et al.
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Cell death: Critical control points
NN Danial et al.
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XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer
C Cao et al.
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Vaccination with p53-peptide-pulsed dendritic cells, of patients with advanced breast cancer: report from a phase I study
IM Svane et al.
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Morphological features of cell death
U Ziegler et al.
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Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance
E Devarajan et al.
ONCOGENE (2002)
Characterization of the p53-rescue drug CP-31398 in vitro and in living cells
TM Rippin et al.
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Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern
Y Ashhab et al.
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ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
D Vucic et al.
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