期刊
JOURNAL OF EVOLUTIONARY BIOLOGY
卷 21, 期 6, 页码 1844-1851出版社
WILEY
DOI: 10.1111/j.1420-9101.2008.01608.x
关键词
cytonuclear genic incompatibility; hybrid breakdown; hybrid inviability; mitochondria; oxidative phosphorylation; speciation
资金
- NIH marine biotechnology
- NIH-NCRR [1R21 RR024199-01)]
Male F-2 hybrids of the wasps Nasonia giraulti and Nasonia vitripennis suffer increased mortality during development. Previous studies suggested that the mitochondria may play an important role in this pattern of hybrid breakdown. The mitochondrial genome encodes 13 polypeptides, which are integral subunits of the oxidative phosphorylation enzyme complexes I, III, IV and V. We show that the mitochondrial ATP production rate and the efficacy of the enzyme complexes I, III and IV, but not that of the completely nuclear-encoded complex II, are reduced in F-2 hybrid males of N. giraulti and N. vitripennis. We hypothesize that nuclear-mitochondrial protein interactions in the oxidative phosphorylation pathway are disrupted in these hybrids, reducing energy generation capacity and potentially reducing hybrid fitness. Our results suggest that dysfunctional cytonuclear interactions could represent an under-appreciated post-zygotic isolation mechanism that, due to elevated evolutionary rates of mitochondrial genes, evolves very early in the speciation process.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据