4.6 Article

Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Molecular dynamics simulations on the critical states of the farnesyltransferase enzyme

Sergio Filipe Sousa et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors

Kohsuke Asoh et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

Article Chemistry, Medicinal

Synthesis of potent antitumor and antiviral benzofuran derivatives

Shadia A. Galal et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

Article Chemistry, Multidisciplinary

The Search for the Mechanism of the Reaction Catalyzed by Farnesyltransferase

Sergio Filipe Sousa et al.

CHEMISTRY-A EUROPEAN JOURNAL (2009)

Article Chemistry, Physical

Unraveling the Catalytic Pathway of Metalloenzyme Farnesyltransferase through QM/MM Computation

Ming-Hsun Ho et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)

Article Biochemistry & Molecular Biology

Similarity-based SIBAR descriptors for classification of chemically diverse hERG blockers

Khac-Minh Thai et al.

MOLECULAR DIVERSITY (2009)

Article Biochemistry & Molecular Biology

On Two Novel Parameters for Validation of Predictive QSAR Models

Partha Pratim Roy et al.

MOLECULES (2009)

Review Biochemistry & Molecular Biology

Farnesyltransferase inhibitors: A detailed chemical view on an elusive biological problem

Sergio F. Sousa et al.

CURRENT MEDICINAL CHEMISTRY (2008)

Article Chemistry, Physical

Molecular dynamics analysis of farnesyltransferase: A closer look into the amino acid behavior

Sergio F. Sousa et al.

INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY (2008)

Article Chemistry, Physical

Enzyme flexibility and the catalytic mechanism of farnesyltransferase: Targeting the relation

Sergio F. Sousa et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2008)

Article Chemistry, Medicinal

On some aspects of variable selection for partial least squares regression models

Partha Pratim Roy et al.

QSAR & COMBINATORIAL SCIENCE (2008)

Article Biochemistry & Molecular Biology

Analysis of zinc-ligand bond lengths in metalloproteins: Trends and patterns

Bruno Tamames et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)

Article Social Sciences, Interdisciplinary

A caution regarding rules of thumb for variance inflation factors

Robert M. O'Brien

QUALITY & QUANTITY (2007)

Article Chemistry, Multidisciplinary

Theoretical studies on farnesyltransferase: Evidence for thioether product coordination to the active-site zinc sphere

Sergio Filipe Sousa et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2007)

Review Chemistry, Medicinal

Principles of QSAR models validation: internal and external

Paola Gramatica

QSAR & COMBINATORIAL SCIENCE (2007)

Article Chemistry, Medicinal

Pharmacophore mapping of diverse classes of farnesyltransferase inhibitors

Tabish Equbal et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Article Biochemistry & Molecular Biology

Exploiting the substrate tolerance of farnesyltransferase for site-selective protein derivatization

Uyen T. T. Nguyen et al.

CHEMBIOCHEM (2007)

Article Biochemistry & Molecular Biology

Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential

Rieko Tanaka et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2007)

Review Biochemistry & Molecular Biology

Theoretical studies on farnesyltransferase: The distances paradox explained

Sergio Filipe Sousa et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)

Review Biochemistry & Molecular Biology

Farnesyl transferase inhibitors

AD Basso et al.

JOURNAL OF LIPID RESEARCH (2006)

Article Chemistry, Physical

Farnesyltransferase: Theoretical studies on peptide substrate entrance thiol or thiolate coordination?

SF Sousa et al.

JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM (2005)

Article Chemistry, Medicinal

BCUT descriptors for predicting affinity toward A3 adenosine receptors

MP González et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)

Article Chemistry, Medicinal

Inhibitors of farnesyltransferase: A rational approach to cancer chemotherapy?

IM Bell

JOURNAL OF MEDICINAL CHEMISTRY (2004)

Article Chemistry, Multidisciplinary

2D QSAR consensus prediction for high-throughput virtual screening. An application to COX-2 inhibition modeling and screening of the NCI database

N Baurin et al.

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2004)

Article Chemistry, Multidisciplinary

Structural characterization of the zinc site in protein farnesyltransferase

DA Tobin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

Article Biochemistry & Molecular Biology

Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation

JS Pickett et al.

BIOCHEMISTRY (2003)

Review Chemistry, Medicinal

Farnesyl protein transferase inhibitor ZARNESTRA (TM) R115777 - History of a discovery

M Venet et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Reaction path of protein farnesyltransferase at atomic resolution

SB Long et al.

NATURE (2002)

Article Biochemical Research Methods

Beware of q(2)!

A Golbraikh et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2002)

Article Multidisciplinary Sciences

The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics

SB Long et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Chemistry, Multidisciplinary

Application of BCUT metrics and genetic algorithm in binary QSAR analysis

H Gao

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2001)

Article Biochemistry & Molecular Biology

Farnesylation of nonpeptidic thiol compounds by protein farnesyltransferase

KE Hightower et al.

BIOCHEMISTRY (2001)

Review Chemistry, Medicinal

Inhibitors of protein prenylation 2000

IM Bell

EXPERT OPINION ON THERAPEUTIC PATENTS (2000)

Article Biochemical Research Methods

A widely applicable set of descriptors

P Labute

JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2000)

Article Biochemistry & Molecular Biology

Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei

FS Buckner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)