期刊
JOURNAL OF ENVIRONMENTAL SCIENCES
卷 23, 期 10, 页码 1721-1728出版社
SCIENCE PRESS
DOI: 10.1016/S1001-0742(10)60598-0
关键词
rare earth elements; lanthanum; heat shock protein 70; oxidatively modified proteins; isoenzymes; hormesis; risk assessment
资金
- National Natural Science Foundation of China [20877032]
- Foundation of State Key Laboratory of Pollution Control and Resources Reuse of China [PCRRF08011]
Combined chemical analyses and biological measurements were utilized to investigate potential toxicological effects and possible mechanisms involved in risk assessment of rare earth elements (REEs) on Vicia faba L. seedlings, which were hydroponically cultivated and exposed to various concentrations of lanthanum (La) for 15 days. The results showed that La contents in both the solution and roots increased with the increase of extraneous La, contributing to hormetic dose responses of superoxide dismutase (SOD), catalase (CAT), guaiacol peroxidase (GPX), ascorbate peroxidase (APX) and endoprotease (EP) isozymes activities, and HSP 70 production enhanced at low doses but suppressed at higher doses of La. These physiological responses constituted antioxidant and detoxification systems against La-induced oxidative stress. The elevated La levels also contributed to oxidatively modified proteins, which were most responsible for subsequent cell death and growth retardation of the roots. By combination of hormetic and traditional threshold dose levels, the threshold dose range was deduced to be 108-195 mu g La/g dry weight in the roots, corresponding to 0.90-3.12 mg/L of soluble La in the culture solution. It suggests that persistent applications of REEs may lead to potential ecological risk in the environment.
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