4.1 Article

Herbal Medicines in Neurodegenerative Disorders: An Evolutionary Approach through Novel Drug Delivery System

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BEGELL HOUSE INC
DOI: 10.1615/JEnvironPatholToxicolOncol.2018027246

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Alzheimer's disease; herbal drugs; oxidative stress; mitochondrial dysfunction; novel delivery system

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Neurodegenerative disorders are one of the most debilitating, chronic, and often irreversible disorders of the brain and have gained a widespread attention of researchers. Since current therapeutics seem to be inadequate treatment of these disorders, scientists arc exploring their options with herbal drugs. This review discusses herbal constituents with the potential to treat neurological disorders. These herbal drugs, when combined with a novel delivery system, provide added advantages to nanocarrier systems. The review also presents research on different herbals through liposomes, polymeric nanoparticles, and solid lipid nanoparticles. The data are collected from various online databases, including PubMed, ScienceDirect, references from relevant review articles, and other official publications. Broad search term criteria are followed for searches so that all pertinent information is included.

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