Electrocatalytic oxidation of some amino acids on a cobalt hydroxide nanoparticles modified glassy carbon electrode

In this study we investigated the electrocatalytic oxidation of cysteine, cystine, N-acetyl cysteine, and methionine on cobalt hydroxide nanoparticles modified glassy carbon electrode in alkaline solution. Different electrochemical techniques such as cyclic voltammetry, chronoamperometry and steady-state polarization were used to track the oxidation process and its kinetics. From voltammetric studies we concluded that in the presence of amino acids the anodic peak current of Co(IV) species increased, followed by a decrease in the corresponding cathodic current peak. This indicates that amino acids were oxidized on the redox mediator which was immobilized on the electrode surface via an electrocatalytic mechanism. Using Laviron's equation, the values of alpha(s) and k(s) for the immobilized redox species were determined as alpha(s,a) = 0.63, alpha(s,c) = 0.38 and k(s) = 0.28 s(-1), respectively. The catalytic rate constants, the electron transfer coefficients and the diffusion coefficients involved in the electrocatalytic oxidation of amino acids were determined. (C) 2010 Elsevier B.V. All rights reserved.