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Overexpression of the prolyl isomerase PIN1 promotes cell growth in osteosarcoma cells
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Osteoporosis, jawbones and periodontal disease
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Nicotine and lipopolysaccharide stimulate the production of MMPs and prostaglandin E2 by hypoxia-inducible factor-1α up-regulation in human periodontal ligament cells
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Overexpression of peptidyl-prolyl isomerase Pin1 attenuates hepatocytes apoptosis and secondary necrosis following carbon tetrachloride-induced acute liver injury in mice
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Role of Pin1 in UVA-induced cell proliferation and malignant transformation in epidermal cells
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Anti-inflammatory effects of lindenenyl acetate via heme oxygenase-1 and AMPK in human periodontal ligament cells
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SIRT1 Modulates High-Mobility Group Box 1-Induced Osteoclastogenic Cytokines in Human Periodontal Ligament Cells
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Heme oxygenase-1 mediates nicotine- and lipopolysaccharide-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in human periodontal ligament cells
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The Pin 1 inhibitor juglone attenuates kidney fibrogenesis via Pin 1-independent mechanisms in the unilateral ureteral occlusion model
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Anti-inflammatory effects of apigenin on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1
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The peptidyl-prolyl isomerase, Pin1, facilitates NF-κB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury
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Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance
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The prolyl isomerase Pin1 regulates the NF-κB signaling pathway and interleukin-8 expression in glioblastoma
G. P. Atkinson et al.
ONCOGENE (2009)
The rotamase Pin1 is up-regulated, hypophosphorylated and required for cell cycle progression in head and neck squamous cell carcinomas
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A critical role for Pin1 in allergic pulmonary eosinophilia in rats
Stephane Esnault et al.
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Gingival crevicular fluid prostaglandin E-2 and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen
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JOURNAL OF PERIODONTOLOGY (2007)
The impact of cigarette smoking on periodontal disease and treatment
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PERIODONTOLOGY 2000 (2007)
Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cells by increasing macrophage colony-stimulating factor and prostaglandin E2 production by osteoblasts
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Nitric oxide synthase inhibition prevents alveolar bone resorption in experimental periodontitis in rats
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MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1α
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JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Selective inhibition of NF-κB blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo
E Jimi et al.
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Regulation of NF-kappa B signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
A Ryo et al.
MOLECULAR CELL (2003)
PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells
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MOLECULAR AND CELLULAR BIOLOGY (2002)
Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription
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NUCLEIC ACIDS RESEARCH (2001)
Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction
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