期刊
JOURNAL OF CYSTIC FIBROSIS
卷 13, 期 4, 页码 410-415出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jcf.2013.12.002
关键词
Cystic fibrosis; Survival; Mortality; Healthcare
资金
- Wellcome Trust [WT092295AIA]
- NIHR [DRF-2009-02-112]
- National Institute for Health Research [PB-PG-1207-15025, DRF-2009-02-112] Funding Source: researchfish
- National Institutes of Health Research (NIHR) [PB-PG-1207-15025] Funding Source: National Institutes of Health Research (NIHR)
Background: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement. Method: Death registration data analysis (US, England & Wales (E&W)-1972-2009). Results: CF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed. Conclusion: The median age of death of people with CF is improving more rapidly than that of the general population in US and E&W. (C) 2013 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
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